Group interpersonal psychotherapy for depression in rural Uganda: 6-Month outcomes: Randomised controlled trial

Judith Bass, Richard Neugebauer, Kathleen F. Clougherty, Helen Verdeli, Priya Wickramaratne, Lincoln Ndogoni, Liesbeth Speelman, Myrna Weissman, Paul Bolton

Research output: Contribution to journalArticle

Abstract

Background: A randomised controlled trial comparing group interpersonal psychotherapy with treatment as usual among rural Ugandans meeting symptom and functional impairment criteria for DSM-IV major depressive disorder or sub-threshold disorder showed evidence of effectiveness immediately following the intervention. Aims: To assess the long-term effectiveness of this therapy over a subsequent 6-month period. Method: A follow-up study of trial participants was conducted in which the primary outcomes were depression diagnosis, depressive symptoms and functional impairment. Results: At 6 months, participants receiving the group interpersonal psychotherapy had mean depression symptom and functional impairment scores respectively 14.0 points (95% CI 12.2-15.8; P < 0.0001) and 5.0 points (95% CI 3.6-6.4; P < 0.0001) lower than the control group. Similarly, the rate of major depression among those in the treatment arm (11.7%) was significantly lower than that in the control arm (54.9%) (P < 0.0001). Conclusions: Participation in a 16-week group interpersonal psychotherapy intervention continued to confer a substantial mental health benefit 6 months after conclusion of the formal intervention.

Original languageEnglish (US)
Pages (from-to)567-573
Number of pages7
JournalBritish Journal of Psychiatry
Volume188
Issue numberJUNE
DOIs
StatePublished - Jun 1 2006
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health

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    Bass, J., Neugebauer, R., Clougherty, K. F., Verdeli, H., Wickramaratne, P., Ndogoni, L., Speelman, L., Weissman, M., & Bolton, P. (2006). Group interpersonal psychotherapy for depression in rural Uganda: 6-Month outcomes: Randomised controlled trial. British Journal of Psychiatry, 188(JUNE), 567-573. https://doi.org/10.1192/bjp.188.6.567