Group C rotavirus infections in patients with diarrhea in Thailand, Nepal, and England

Maria E. Peãaranda, W. David Cubitt, Pantipa Sinarachatanant, David N. Taylor, Sirirat Likanonsakul, Linda Saif, Roger I. Glass

Research output: Contribution to journalArticle

Abstract

Atypical rotavirus obtained from fecal specimens of six patients with diarrhea from Thailand, Nepal, and England were characterized by using polyacrylamide gel electrophoresis and immune electron microscopy. The electropherotypes were characteristic of the porcine reference group C rotavirus strain but demonstrated considerable strain-to-strain variation. Human convalescent group C sera had a high titer (l:320) when tested against the human isolates and a low titer (l:40) when tested against a porcine reference strain (Cowden). When porcine antiserum (Cowden) was tested against the human isolates, the titers ranged from 1:40to 1:320, indicating significant antigenic diversity between strains. Group C rotavirus appears to have a worldwide distribution as an agent associated with diarrhea in children and adults.

Original languageEnglish (US)
Pages (from-to)392-397
Number of pages6
JournalJournal of Infectious Diseases
Volume160
Issue number3
DOIs
StatePublished - 1989
Externally publishedYes

Fingerprint

Rotavirus Infections
Nepal
Rotavirus
Thailand
England
Diarrhea
Swine
Antigenic Variation
Immune Sera
Polyacrylamide Gel Electrophoresis
Electron Microscopy
Serum

ASJC Scopus subject areas

  • Infectious Diseases
  • Immunology and Allergy
  • Immunology
  • Public Health, Environmental and Occupational Health

Cite this

Peãaranda, M. E., David Cubitt, W., Sinarachatanant, P., Taylor, D. N., Likanonsakul, S., Saif, L., & Glass, R. I. (1989). Group C rotavirus infections in patients with diarrhea in Thailand, Nepal, and England. Journal of Infectious Diseases, 160(3), 392-397. https://doi.org/10.1093/infdis/160.3.392

Group C rotavirus infections in patients with diarrhea in Thailand, Nepal, and England. / Peãaranda, Maria E.; David Cubitt, W.; Sinarachatanant, Pantipa; Taylor, David N.; Likanonsakul, Sirirat; Saif, Linda; Glass, Roger I.

In: Journal of Infectious Diseases, Vol. 160, No. 3, 1989, p. 392-397.

Research output: Contribution to journalArticle

Peãaranda, ME, David Cubitt, W, Sinarachatanant, P, Taylor, DN, Likanonsakul, S, Saif, L & Glass, RI 1989, 'Group C rotavirus infections in patients with diarrhea in Thailand, Nepal, and England', Journal of Infectious Diseases, vol. 160, no. 3, pp. 392-397. https://doi.org/10.1093/infdis/160.3.392
Peãaranda ME, David Cubitt W, Sinarachatanant P, Taylor DN, Likanonsakul S, Saif L et al. Group C rotavirus infections in patients with diarrhea in Thailand, Nepal, and England. Journal of Infectious Diseases. 1989;160(3):392-397. https://doi.org/10.1093/infdis/160.3.392
Peãaranda, Maria E. ; David Cubitt, W. ; Sinarachatanant, Pantipa ; Taylor, David N. ; Likanonsakul, Sirirat ; Saif, Linda ; Glass, Roger I. / Group C rotavirus infections in patients with diarrhea in Thailand, Nepal, and England. In: Journal of Infectious Diseases. 1989 ; Vol. 160, No. 3. pp. 392-397.
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