Group C rotavirus infections in patients with diarrhea in Thailand, Nepal, and England

Maria E. Peãaranda, W. David Cubitt, Pantipa Sinarachatanant, David N. Taylor, Sirirat Likanonsakul, Linda Saif, Roger I. Glass

Research output: Contribution to journalArticlepeer-review


Atypical rotavirus obtained from fecal specimens of six patients with diarrhea from Thailand, Nepal, and England were characterized by using polyacrylamide gel electrophoresis and immune electron microscopy. The electropherotypes were characteristic of the porcine reference group C rotavirus strain but demonstrated considerable strain-to-strain variation. Human convalescent group C sera had a high titer (l:320) when tested against the human isolates and a low titer (l:40) when tested against a porcine reference strain (Cowden). When porcine antiserum (Cowden) was tested against the human isolates, the titers ranged from 1:40to 1:320, indicating significant antigenic diversity between strains. Group C rotavirus appears to have a worldwide distribution as an agent associated with diarrhea in children and adults.

Original languageEnglish (US)
Pages (from-to)392-397
Number of pages6
JournalJournal of Infectious Diseases
Issue number3
StatePublished - Sep 1989

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases


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