Griscelli syndrome: Report of three cases

Safiye Gögbreve;uuml;scedil;, Meral Topçu, Türkan Küccedil;uuml;kali, Zuhal Akçouml;ren, Izzet Berkel, Figen Ersoy, Meral Günay, Işil Saatçi

Research output: Contribution to journalArticle

Abstract

The clinical features of three children with Griscelli syndrome and autopsy findings of two are presented. The patients were 5 years, 9 months, and 3 months old, respectively. Clinical features included partial albinism, hepatosplenomegaly, and various neurological symptoms. Light and electron microscopic studies of the skin were compatible with Griscelli syndrome. Postmortem examination of the viscera and central nervous system revealed lymphohistiocytic infiltration with erythrophagocytosis. Bilateral diffuse involvement of the central nervous system, cranial nerve, and spinal cord was detected in both cases..

Original languageEnglish (US)
Pages (from-to)309-319
Number of pages11
JournalFetal and Pediatric Pathology
Volume15
Issue number2
DOIs
StatePublished - Jan 1 1995

    Fingerprint

Keywords

  • Griscelli syndrome
  • Hemophagocytosis
  • Lymphohistiocytosis
  • Partial albinism

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pathology and Forensic Medicine

Cite this

Gögbreve;uuml;scedil;, S., Topçu, M., Küccedil;uuml;kali, T., Akçouml;ren, Z., Berkel, I., Ersoy, F., Günay, M., & Saatçi, I. (1995). Griscelli syndrome: Report of three cases. Fetal and Pediatric Pathology, 15(2), 309-319. https://doi.org/10.3109/15513819509026966