Granulomatous interstitial nephritis associated with bone marrow transplantation

Andrew L. Schwaderer, Lois Arend, Marc B. Lande

Research output: Contribution to journalArticlepeer-review

Abstract

We describe two brothers with severe combined immunodeficiency, who presented with systemic granulomatous disease, with granulomatous interstitial nephritis as the main feature, several years following bone marrow transplantation. Neither brother had an apparent drug-induced, infectious disease or autoimmune source for the granulomatous interstitial nephritis. Both patients' renal function improved following treatment with corticosteroids. This report implicates granulomatous interstitial nephritis as a complication of bone marrow transplantation for severe combined immunodeficiency.

Original languageEnglish (US)
Pages (from-to)539-542
Number of pages4
JournalPediatric Nephrology
Volume20
Issue number4
DOIs
StatePublished - Apr 1 2005

Keywords

  • Corticosteroids
  • Graft versus host disease
  • Renal granuloma
  • Sarcoidosis
  • Severe combined immunodeficiency

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Nephrology

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