Gradient-enhanced heteronuclear correlation spectroscopy. Theory and experimental aspects

Jesus Ruiz-Cabello, Geerten W. Vuister, Chrit T.W. Moonen, Peter van Gelderen, Jack S. Cohen, Peter C.M. van Zijl

Research output: Contribution to journalArticlepeer-review

233 Scopus citations


A detailed theoretical and experimental treatment is given for gradient-enhanced heteronuclear correlation spectroscopy. Both multiple-quantum and single-quantum sequences are described. In addition to a comparison with conventional experiments using phase cycling, the effects of different gradient combinations are examined with respect to artifacts occurring in the heteronuclear dimension. The influence of gradient performance and diffusion on sensitivity is discussed. Approaches to attain phase-sensitive spectra are also analyzed.

Original languageEnglish (US)
Pages (from-to)282-302
Number of pages21
JournalJournal of Magnetic Resonance (1969)
Issue number2
StatePublished - Nov 1992
Externally publishedYes


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