Gonorrhoea reinfection in heterosexual STD clinic attendees: Longitudinal analysis of risks for first reinfection

S. D. Mehta, E. J. Erbelding, Jonathan Mark Zenilman, Anne Marie Rompalo

Research output: Contribution to journalArticle

Abstract

Objectives: Gonorrhoea is associated with adverse reproductive health outcomes, including pelvic inflammatory disease and increased HIV transmission. Our objective was to determine the association of demographic factors, sexual risk behaviours, and drug use with incident gonorrhoea reinfection among public STD clinic clients. Methods: A retrospective cohort study conducted from January 1994 through October 1998, of heterosexual public STD clinic attendees age ≥12 years having at least one gonorrhoea infection in Baltimore, MD. The outcome was first incident gonorrhoea reinfection over a maximum 4.8 years, compared in STD clinic clients with or without sexual risk behaviours and drug use at initial gonorrhoea infection. Results: 910 reinfections occurred among 8327 individuals and 21 246 person years of observation, for an overall incidence of 4.28 reinfections per 100 person years (95% CI 4.03 to 4.53). Median time to reinfection was 1.00 year (95% CI 0.91 to 1.07 years). In multivariate Cox regression, increased reinfection risk was associated with male sex, younger age, greater number of recent sex partners, and having a sex partner who is a commercial sex worker. Injection drug use and coming to the clinic as an STD contact were protective. Among risk factors that differed significanlly between men and women, injection drug use was protective of reinfection in men, and "any" condom use was a risk factor for reinfection in women Conclusions: Reinfection represents a significant proportion of STD clinic visits for gonorrhoea. Prevention counselling and routine screening for patients at high risk for reinfection should be considered to maximally reduce transmission and resource utilisation.

Original languageEnglish (US)
Pages (from-to)124-128
Number of pages5
JournalSexually Transmitted Infections
Volume79
Issue number2
DOIs
StatePublished - Apr 2003

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Gonorrhea
Heterosexuality
Sexually Transmitted Diseases
Risk-Taking
Sexual Behavior
Pharmaceutical Preparations
Pelvic Inflammatory Disease
Baltimore
Sex Workers
Injections
Reproductive Health
Condoms
Ambulatory Care
Infection
Counseling
Cohort Studies
Retrospective Studies
Observation
Demography
HIV

ASJC Scopus subject areas

  • Dermatology
  • Microbiology (medical)
  • Immunology

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Gonorrhoea reinfection in heterosexual STD clinic attendees : Longitudinal analysis of risks for first reinfection. / Mehta, S. D.; Erbelding, E. J.; Zenilman, Jonathan Mark; Rompalo, Anne Marie.

In: Sexually Transmitted Infections, Vol. 79, No. 2, 04.2003, p. 124-128.

Research output: Contribution to journalArticle

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