Gonadotropin stimulation for in vitro fertilization and embryo transfer in insulin-dependent diabetics: Follicular response, oocyte quality, embryo development, and follicular environment

S. Oehninger, G. E. Hofmann, D. Kreiner, A. A. Acosta, S. J. Muasher

Research output: Contribution to journalArticle

Abstract

Two IDD patients were stimulated with gonadotropins for IVF and ET. Both patients had high E2 response and ≥5 preovulatory oocytes retrieved, normal fertilization and cleavage rates, and transfer; neither conceived. Follicular fluid showed levels of E2, P, A, hCG, and PRL similar to non-IDD. Epidermal growth factor could not be detected in FF. Insulin-dependent diabetes patients can undergo gonadotropin stimulation for IVF with customary responses. Their follicular milieu resembles that of non-IDD patients except for a lack of EGF.

Original languageEnglish (US)
Pages (from-to)741-743
Number of pages3
JournalFertility and sterility
Volume53
Issue number4
DOIs
StatePublished - Jan 1 1990

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ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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