Gonadotropin response to luteinizing hormone releasing hormone administration in secondary amenorrhea and galactorrhea syndromes

Anne Colston Wentz, Georgeanna Seegar Jones, Laura Rocco, Robert R. Matthews

Research output: Contribution to journalArticle

Abstract

Luteinizing hormone releasing hormone (LMRH), 100μg, was administered to 60 patients with secondary amenorrhea. No side effects or adverse reactions occurred. Delayed FSH and LH peak outputs were observed in patients receiving LHRH subcutaneously rather than intravenously, but responses were otherwise comparable. The majority of patients with secondary amenorrhea had responses which fell into the 95% confidence limits of responses for normal ovulating women. Responses of patients with different forms of dysfunction may be similar, and patients with similar pathology may respond quite differently. The LHRH stimulation test may assist in the diagnosis of particular hypothalamic, pituitary, or gonadal dysfunction, but it must be used clinically in the context of a carefully integrated study.

Original languageEnglish (US)
Pages (from-to)256-262
Number of pages7
JournalObstetrics and gynecology
Volume45
Issue number3
StatePublished - Mar 1975

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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