Gonadal hormone levels in injection drug users

Justin T. Wahlstrom, Alice Tang, Joseph Cofrancesco, Nina Shah, Adrian S. Dobs

Research output: Contribution to journalArticlepeer-review

Abstract

Levels of serum sex hormones, particularly testosterone, luteinizing hormone, and follicle-stimulating hormone, have been shown to change in various disease states. Hypogonadism has been well-documented in patients with HIV infection. As HIV infection and injection drug use are closely linked, we examined whether injection drug users (IDU's) exhibit hormone abnormalities. We evaluated men participating in the ALIVE study (AIDS Linked to Intravenous Experiences), a large cohort study conducted in Baltimore, MD. We found that 20% of 40 IDU subjects (20 HIV+, 20 HIV-) with a mean age 41.5±0.9, had low serum total testosterone concentration. We were unable to detect a direct correlation between drug use and hormone levels. Further study is needed on the hormonal milieu of the IDU patient. Copyright (C) 2000 Elsevier Science Ireland Ltd.

Original languageEnglish (US)
Pages (from-to)311-313
Number of pages3
JournalDrug and alcohol dependence
Volume60
Issue number3
DOIs
StatePublished - Nov 10 2000

Keywords

  • Endocrinology
  • HIV status
  • Injection drug use
  • Testosterone

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology
  • Psychiatry and Mental health
  • Pharmacology (medical)

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