Gold nanocages as contrast agents for two-photon luminescence endomicroscopy imaging

Yongping Chen, Yuying Zhang, Wenxuan Liang, Xingde Li

Research output: Contribution to journalArticle

Abstract

We explored the possibility of using gold (Au) nanocages as a new class of exogenous contrast agents for endomicroscopic nonlinear imaging. The two-photon luminescence cross-section of nanocages was characterized. Two-photon luminescence endomicroscopy imaging of a phantom, cancer cells and biological tissues was performed, demonstrating that Au nanocages can potentially serve as an effective molecular contrast agent for nonlinear endomicroscopy imaging. From the Clinical Editor: In this study, the utility of Au nanocages is described in a variety of settings as effective molecular contrast agent for nonlinear endomicroscopy imaging.

Original languageEnglish (US)
Pages (from-to)1267-1270
Number of pages4
JournalNanomedicine: Nanotechnology, Biology, and Medicine
Volume8
Issue number8
DOIs
StatePublished - Nov 1 2012

Keywords

  • Contrast agents
  • Endomicroscopy
  • Gold nanocages
  • Two-photon luminescence imaging

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Molecular Medicine
  • Biomedical Engineering
  • Materials Science(all)
  • Pharmaceutical Science

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