Goblet cell population among patients with inactive trachoma

Barbara A. Blodi, Kathleen A. Byrne, Khalid F. Tabbara

Research output: Contribution to journalArticle

Abstract

Trachoma is a chlamydial disease that affects millions of people each year, particularly in developing countries. In the chronic phase, inflammation causes scarring of the conjunctiva followed by dry eye which can result in blindness. Trachoma may cause dryness of the eye by decreasing mucus production and aqueous secretions. Conjunctival impression cytology was carried out to determine the goblet cell population among patients with trachoma. We performed impression cytology on 32 patients with inactive trachoma and 31 age and sex matched controls. Impression cytology showed that the nasal conjunctiva contains the greatest number of goblet cells. Trachoma patients with severe scarring had significantly less goblet cell counts than those with mild scarring (p

Original languageEnglish (US)
Pages (from-to)41-45
Number of pages5
JournalInternational Ophthalmology
Volume12
Issue number1
DOIs
StatePublished - Mar 1988
Externally publishedYes

Keywords

  • dry eye syndrome
  • goblet cells
  • keratoconjunctivitis sicca
  • mucus deficiency
  • trachoma

ASJC Scopus subject areas

  • Ophthalmology

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