Glycemic control and sliding scale insulin use in medical inpatients with diabetes mellitus

William S. Queale, Alexander J. Seidler, Frederick L. Brancati

Research output: Contribution to journalArticle

Abstract

Objective: To identify predictors of hypoglycemic and hyperglycemic episodes in hospitalized patients with diabetes with special attention to the effectiveness of sliding scale insulin regimens. Design: Prospective cohort study. Setting: Urban university hospital. Participants: One hundred seventy- one adults with diabetes mellitus as a comorbid condition admitted consecutively to medical inpatient services during a 7-week period. Measurements: Demographic, clinical, and laboratory data from inpatient medical records. Main Outcomes: Rates of hypoglycemic (capillary blood glucose, ≤3.3 mmol/L [≤60 mg/dL]) and hyperglycemic (capillary blood glucose, ≤ 16.5 mmol/L [ ≤ 300 mg/dL]) episodes. Results: Of the patients, 23% experienced hypoglycemic episodes, and 40% experienced hyperglycemic episodes. The overall rates of hypoglycemic and hyperglycemic episodes were 3.4 and 9.8 per 100 capillary blood glucose measurements, respectively. Independent predictors of hypoglycemic episodes included African American race (relative risk [RR], 2.13) and low serum albumin level (RR, 1.92 per 100-g/L decrease); corticosteroid use was associated with a reduced risk of hypoglycemic episodes (RR. 0.32; P

Original languageEnglish (US)
Pages (from-to)545-552
Number of pages8
JournalArchives of Internal Medicine
Volume157
Issue number5
StatePublished - 1997

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Hypoglycemic Agents
Inpatients
Diabetes Mellitus
Insulin
Blood Glucose
Urban Hospitals
Serum Albumin
African Americans
Medical Records
Adrenal Cortex Hormones
Cohort Studies
Demography
Prospective Studies

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Glycemic control and sliding scale insulin use in medical inpatients with diabetes mellitus. / Queale, William S.; Seidler, Alexander J.; Brancati, Frederick L.

In: Archives of Internal Medicine, Vol. 157, No. 5, 1997, p. 545-552.

Research output: Contribution to journalArticle

Queale, WS, Seidler, AJ & Brancati, FL 1997, 'Glycemic control and sliding scale insulin use in medical inpatients with diabetes mellitus', Archives of Internal Medicine, vol. 157, no. 5, pp. 545-552.
Queale, William S. ; Seidler, Alexander J. ; Brancati, Frederick L. / Glycemic control and sliding scale insulin use in medical inpatients with diabetes mellitus. In: Archives of Internal Medicine. 1997 ; Vol. 157, No. 5. pp. 545-552.
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