Glutamate transporters in neurologic disease

Research output: Contribution to journalArticle

Abstract

Glutamate is the primary excitatory amino acid neurotransmitter in the human brain. It is important in synaptic plasticity, learning, and development. Its activity at the synaptic cleft is carefully balanced by receptor inactivation and glutamate reuptake. When this balance is upset, excess glutamate can itself become neurotoxic.

Original languageEnglish (US)
Pages (from-to)365-370
Number of pages6
JournalArchives of Neurology
Volume58
Issue number3
StatePublished - 2001

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Amino Acid Transport System X-AG
Nervous System Diseases
Glutamic Acid
Excitatory Amino Acids
Neuronal Plasticity
Glutamate Receptors
Neurotransmitter Agents
Learning
Brain
Cleft
Excess
Amino Acids
Plasticity

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Glutamate transporters in neurologic disease. / Maragakis, Nicholas J; Rothstein, Jeffrey D.

In: Archives of Neurology, Vol. 58, No. 3, 2001, p. 365-370.

Research output: Contribution to journalArticle

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