Glutamate recognition sites in human fetal brain

John D. Barks, Faye S. Silverstein, Katherine Sims, J. Timothy Greenamyre, Michael V. Johnston

Research output: Contribution to journalArticlepeer-review

Abstract

We used in vitro autoradiography with [3H]glutamate to examine the distribution of glutamate recognition sites in 18 and 21 week gestation human fetal brains. We found a wide distribution of [3H]glutamate binding in both specimens, in a pattern distinct from that reported in adult brain using the same autoradiographic methods. In fetal brain, prominent [3H]glutamate binding was evident in hippocampal formation, caudate-putamen, globus pallidus, subthalamic nucleus, reticular nucleus of thalamus and substantia innominata.

Original languageEnglish (US)
Pages (from-to)131-136
Number of pages6
JournalNeuroscience Letters
Volume84
Issue number2
DOIs
StatePublished - Jan 22 1988
Externally publishedYes

Keywords

  • Autoradiography
  • Caudate
  • Fetus
  • Globus pallidus
  • Glutamate
  • Hippocampus
  • Human

ASJC Scopus subject areas

  • Neuroscience(all)

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