Glucose metabolism in cancer

Sminu Bose, Quy Hoa Le Thi

Research output: Chapter in Book/Report/Conference proceedingChapter


Tumor cells exhibit an upregulation in glycolysis, glycogen metabolism, and gluconeogenesis as opposed to normal cells.The metabolic reprogramming underlying the Warburg effect and other changes in glucose metabolism are driven by several oncogenes and tumor suppressors.Numerous therapies based on cancer metabolism have been developed but have yet to show success in clinical trials.

Original languageEnglish (US)
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Number of pages10
StatePublished - Jan 1 2018

Publication series

NameAdvances in Experimental Medicine and Biology
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019


  • Cancer metabolism
  • Gluconeogenesis
  • Glucose metabolism
  • Glycogenolysis
  • Warburg effect

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Bose, S., & Le Thi, Q. H. (2018). Glucose metabolism in cancer. In Advances in Experimental Medicine and Biology (pp. 3-12). (Advances in Experimental Medicine and Biology; Vol. 1063). Springer New York LLC.