Glucose-lowering drugs to reduce cardiovascular risk in type 2 diabetes

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2 Scopus citations

Abstract

A 64-year-old woman with a 10-year history of type 2 diabetes presents for a routine wellness visit. She had a myocardial infarction 4 years ago and has well-controlled hypertension and dyslipidemia. Her medications include 2000 mg of metformin daily, losartan, hydrochlorothiazide, high-intensity atorvastatin, and aspirin. She does not monitor her blood glucose levels routinely at home. On examination, her blood pressure is 128/75 mm Hg and her body-mass index (the weight in kilograms divided by the square of the height in meters) is 33. Her glycated hemoglobin level is 7.9%, total cholesterol level 155 mg per deciliter (4.0 mmol per liter), high-density lipoprotein cholesterol level 52 mg per deciliter (1.34 mmol per liter), triglyceride level 126 mg per deciliter (1.4 mmol per liter), and low-density lipoprotein cholesterol level 78 mg per deciliter (2.0 mmol per liter). The estimated glomerular filtration rate is 76 ml per minute per 1.73 m2 of body-surface area, and the urinary albumin-to-creatinine ratio (with albumin measured in milligrams and creatinine in grams) is 25. She has no retinopathy or neuropathy. She has heard that certain medications for diabetes can reduce her risk of cardiovascular disease. What would you advise?

Original languageEnglish (US)
Pages (from-to)1248-1260
Number of pages13
JournalNew England Journal of Medicine
Volume384
Issue number13
DOIs
StatePublished - Apr 1 2021

ASJC Scopus subject areas

  • General Medicine

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