TY - JOUR
T1 - Glucosamine and chondroitin sulfate are effective in the management of osteoarthritis
AU - Hungerford, David S.
AU - Jones, Lynne C.
PY - 2003/4
Y1 - 2003/4
N2 - The use of glucosamine and chondroitin sulfate for the symptomatic treatment of osteoarthritis has been a subject of controversy for several reasons. First, the medical community in general took offense at the title of Theodosakis' book, The Arthritis Cure. Second, the medical community is becoming divided into "traditional" and "alternative" camps with deep skepticism between them. Third, the whole nutraceutical industry is essentially unregulated, with manufacturers making outrageous claims on products that have never been tested at all, are often of poor quality, and occasionally lacking in any active ingredient. However, for the nutriceuticals evaluated here, there is abundant in vitro, in vivo, animal clinical, and human clinical evidence of both their efficacy and safety. They deserve a prominent place in the armamentarium of nonsurgical treatment of osteoarthritis.
AB - The use of glucosamine and chondroitin sulfate for the symptomatic treatment of osteoarthritis has been a subject of controversy for several reasons. First, the medical community in general took offense at the title of Theodosakis' book, The Arthritis Cure. Second, the medical community is becoming divided into "traditional" and "alternative" camps with deep skepticism between them. Third, the whole nutraceutical industry is essentially unregulated, with manufacturers making outrageous claims on products that have never been tested at all, are often of poor quality, and occasionally lacking in any active ingredient. However, for the nutriceuticals evaluated here, there is abundant in vitro, in vivo, animal clinical, and human clinical evidence of both their efficacy and safety. They deserve a prominent place in the armamentarium of nonsurgical treatment of osteoarthritis.
KW - Cartilage
KW - Chondroitin sulfate
KW - Glucosamine
KW - Nutraceuticals
KW - Osteoarthritis
UR - http://www.scopus.com/inward/record.url?scp=0038304589&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0038304589&partnerID=8YFLogxK
U2 - 10.1054/arth.2003.50067
DO - 10.1054/arth.2003.50067
M3 - Article
C2 - 12730919
AN - SCOPUS:0038304589
VL - 18
SP - 5
EP - 9
JO - Journal of Arthroplasty
JF - Journal of Arthroplasty
SN - 0883-5403
IS - 3 SUPPL. 1
ER -