Global Analysis of Intercellular Homeodomain Protein Transfer

Eun Jung Lee, Namsuk Kim, Jun Woo Park, Kyung Hwa Kang, Woo il Kim, Nam Suk Sim, Chan Seok Jeong, Seth Blackshaw, Marc Vidal, Sung Oh Huh, Dongsup Kim, Jeong Ho Lee, Jin Woo Kim

Research output: Contribution to journalArticle

Abstract

Lee et al. evaluate capabilities of homeodomain proteins (HPs) for transfer between cells. They find that intercellular transfer is a general but cell-context-sensitive property of HP. Intercellular HP transfer can be an unconventional way for the cells to communicate with neighboring cells that associate structurally and functionally.

Original languageEnglish (US)
Pages (from-to)712-722.e3
JournalCell Reports
Volume28
Issue number3
DOIs
StatePublished - Jul 16 2019

Keywords

  • cell-penetrating protein
  • homeodomain
  • intercellular protein transfer
  • protein secretion

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Lee, E. J., Kim, N., Park, J. W., Kang, K. H., Kim, W. I., Sim, N. S., Jeong, C. S., Blackshaw, S., Vidal, M., Huh, S. O., Kim, D., Lee, J. H., & Kim, J. W. (2019). Global Analysis of Intercellular Homeodomain Protein Transfer. Cell Reports, 28(3), 712-722.e3. https://doi.org/10.1016/j.celrep.2019.06.056