Glioblastoma multiforme masquerading as pseudotumor cerebri: Case report

Maryam Aroichane, Neil R. Miller, Eric R. Eggenberger

Research output: Contribution to journalArticle

Abstract

A 16-year-old girl developed headaches and bilateral papilledema while taking minocycline for acne. The initial neuro-ophthalmologic evaluation was normal except for enlarged blind spots OU. An MRI scan demonstrated subtle abnormalities. A lumbar puncture was entirely normal except for an increased opening pressure. A tentative diagnosis of pseudotumor cerebri was made and the patient was treated with Diamox. A second MRI was unchanged, and a lumbar puncture performed while the patient was taking Diamox was entirely normal. The patient subsequently lost vision in both eyes, and a third MRI now revealed a supracellar enhancing mass. Biopsy and subtotal resection of the mass showed it to be a glioblastoma multiforme. This case emphasizes pitfalls in the diagnosis of pseudotumor cerebri. Careful follow-up and a high index of suspicion in pseudotumor cerebri syndromes are essential.

Original languageEnglish (US)
Pages (from-to)105-112
Number of pages8
JournalJournal of Clinical Neuro-Ophthalmology
Volume13
Issue number2
StatePublished - Jun 1993

Keywords

  • Cerebrospinal fluid cytopathology
  • Cerebrospinal fluid protein
  • Glioblastoma multiforme
  • Minocycline
  • Papilledema
  • Pseudotumor cerebri

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology

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