Giant cell reparative granuloma of the sphenoid bone

Ayse Aralasmak, N. Aygun, W. H. Westra, D. M. Yousem

Research output: Contribution to journalArticle

Abstract

We present 2 patients with giant cell reparative granuloma (GCRG) of the sphenoid bone. The first patient is an 8-year-old boy with involvement of the greater wing, and the second is a 53-year-old man with a lateral pterygoid plate mass. Both patients presented with rapid expansion of lytic bone lesions, which had solid and cystic components and lacked matrix calcification. Biopsies were indeterminate for definitive diagnoses. The radiologic appearance, location, and incidence of the lesions, and the patient's age and medical history are helpful aids in narrowing the differential diagnosis of sphenoid bone lesions. However, the imaging and, occasionally, even the histologic findings may not suggest the specific diagnosis of GCRG, which must be added into the differential diagnosis of rapidly enlarging cystic bone lesions of the sphenoid bone.

Original languageEnglish (US)
Pages (from-to)1675-1677
Number of pages3
JournalAmerican Journal of Neuroradiology
Volume27
Issue number8
StatePublished - Sep 1 2006

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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