Ghrelin-a new player in glucose homeostasis?

Research output: Contribution to journalShort surveypeer-review


The hormone ghrelin regulates secretion of growth hormone and energy homeostasis. Sun et al. (2006), in this issue of Cell Metabolism, demonstrate that ghrelin inhibits insulin secretion. Deletion of ghrelin increased basal insulin level, enhanced glucose-stimulated insulin secretion, and improved peripheral insulin sensitivity. These effects were not related to changes in food intake or weight, suggesting ghrelin has unique actions on key components of glucose homeostasis.

Original languageEnglish (US)
Pages (from-to)301-302
Number of pages2
JournalCell Metabolism
Issue number5
StatePublished - May 2006
Externally publishedYes

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology


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