Gestational diabetes mellitus: Metabolic and blood glucose parameters in singleton versus twin pregnancies

David B. Schwartz, Yahya Daoud, Pauline Zazula, Gregory Goyert, Richard Bronsteen, Debra Wright, Joanna Copes

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVES: This study compared the frequency, glucose tolerance test results, and parameters of blood glucose control in twin and singleton pregnancies associated with gestational diabetes mellitus and carbohydrate intolerance. STUDY DESIGN: Twin and singleton pregnancies associated with gestational diabetes mellitus and carbohydrate intolerance were compared as follows: frequency, maternal age, weight, 1-hour screen, glucose tolerance test results, posttreatment blood glucose values, insulin requirement, and insulin dose. Statistical analysis included the χ2 and Student t tests. RESULTS: Gestational diabetes mellitus was increased in twins (7.7% vs 4.1%; P<.05). The maternal weight at first visit was significantly less, and the 3- hour glucose tolerance test value was significantly greater than that for singletons. The other parameters were not different. CONCLUSIONS: There is a significant increase in the incidence of gestational diabetes mellitus and disturbance of the 3-hour glucose tolerance test in twin pregnancies. However, insulin requirements were not different, suggesting a mild disturbance of carbohydrate tolerance that was effectively managed by the strategies used to achieve blood glucose control in singletons.

Original languageEnglish (US)
Pages (from-to)912-914
Number of pages3
JournalAmerican journal of obstetrics and gynecology
Volume181
Issue number4
DOIs
StatePublished - 1999

Keywords

  • Gestational diabetes
  • Twin pregnancies

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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