TY - JOUR
T1 - Gestational diabetes mellitus
T2 - Metabolic and blood glucose parameters in singleton versus twin pregnancies
AU - Schwartz, David B.
AU - Daoud, Yahya
AU - Zazula, Pauline
AU - Goyert, Gregory
AU - Bronsteen, Richard
AU - Wright, Debra
AU - Copes, Joanna
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1999
Y1 - 1999
N2 - OBJECTIVES: This study compared the frequency, glucose tolerance test results, and parameters of blood glucose control in twin and singleton pregnancies associated with gestational diabetes mellitus and carbohydrate intolerance. STUDY DESIGN: Twin and singleton pregnancies associated with gestational diabetes mellitus and carbohydrate intolerance were compared as follows: frequency, maternal age, weight, 1-hour screen, glucose tolerance test results, posttreatment blood glucose values, insulin requirement, and insulin dose. Statistical analysis included the χ2 and Student t tests. RESULTS: Gestational diabetes mellitus was increased in twins (7.7% vs 4.1%; P<.05). The maternal weight at first visit was significantly less, and the 3- hour glucose tolerance test value was significantly greater than that for singletons. The other parameters were not different. CONCLUSIONS: There is a significant increase in the incidence of gestational diabetes mellitus and disturbance of the 3-hour glucose tolerance test in twin pregnancies. However, insulin requirements were not different, suggesting a mild disturbance of carbohydrate tolerance that was effectively managed by the strategies used to achieve blood glucose control in singletons.
AB - OBJECTIVES: This study compared the frequency, glucose tolerance test results, and parameters of blood glucose control in twin and singleton pregnancies associated with gestational diabetes mellitus and carbohydrate intolerance. STUDY DESIGN: Twin and singleton pregnancies associated with gestational diabetes mellitus and carbohydrate intolerance were compared as follows: frequency, maternal age, weight, 1-hour screen, glucose tolerance test results, posttreatment blood glucose values, insulin requirement, and insulin dose. Statistical analysis included the χ2 and Student t tests. RESULTS: Gestational diabetes mellitus was increased in twins (7.7% vs 4.1%; P<.05). The maternal weight at first visit was significantly less, and the 3- hour glucose tolerance test value was significantly greater than that for singletons. The other parameters were not different. CONCLUSIONS: There is a significant increase in the incidence of gestational diabetes mellitus and disturbance of the 3-hour glucose tolerance test in twin pregnancies. However, insulin requirements were not different, suggesting a mild disturbance of carbohydrate tolerance that was effectively managed by the strategies used to achieve blood glucose control in singletons.
KW - Gestational diabetes
KW - Twin pregnancies
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U2 - 10.1016/S0002-9378(99)70324-8
DO - 10.1016/S0002-9378(99)70324-8
M3 - Article
C2 - 10521752
AN - SCOPUS:0032745446
SN - 0002-9378
VL - 181
SP - 912
EP - 914
JO - American journal of obstetrics and gynecology
JF - American journal of obstetrics and gynecology
IS - 4
ER -