Germline mutations in the alternative pathway of complement predispose to HELLP syndrome

Medicine & Life Sciences

• Alternative Complement Pathway 100%
• Germ-Line Mutation 82%
• Hemolysis 76%
• Blood Platelets 57%
• Enzymes 40%
• Liver 37%
• Atypical Hemolytic Uremic Syndrome 36%
• Pregnancy 14%
• National Heart, Lung, and Blood Institute (U.S.) 11%
• Thrombotic Thrombocytopenic Purpura 10%
• Fetal Mortality 10%
• Gain of Function Mutation 10%
• Mothers 10%
• Morbidity 9%
• Organized Financing 9%
• Genetic Predisposition to Disease 8%
• Genes 6%
• Up-Regulation 5%
• Therapeutics 1%