Geospatial planning and the resulting economic impact of human papillomavirus vaccine introduction in Mozambique

Leila A. Haidari, Shawn T. Brown, Dagna Constenla, Eli Zenkov, Marie Ferguson, Gatien de Broucker , Sachiko Ozawa, Samantha Clark, Allison Portnoy, Bruce Lee

Research output: Contribution to journalArticle

Abstract

Background: Research has shown that the distance to the nearest immunization location can ultimately prevent someone from getting immunized. With the introduction of human papillomavirus (HPV) vaccine throughout the world, a major question is whether the target populations can readily access immunization. Methods: In anticipation of HPV vaccine introduction inMozambique, a country with a 2015 population of 25,727,911, our team developed Strategic Integrated Geo-temporal Mapping Application) to determine the potential economic impact of HPV immunization. We quantified how many people in the target population are reachable by the 1377 existing immunization locations, how many cannot access these locations, and the potential costs and disease burden averted by immunization. Results: If the entire 2015 cohort of 10-year-old girls goes without HPV immunization, approximately 125 (111-139) new cases of HPV 16,18-related cervical cancer are expected in the future. If each health center covers a catchment area with a 5-km radius (ie, if people travel up to 5 km to obtain vaccines), then 40% of the target population could be reached to prevent 50 (44-55) cases, 178 (159-198) disability-adjusted life years, and US $202,854 (US $140,758-323,693) in health care costs and lost productivity. At higher catchment area radii, additional increases in catchment area radius raise population coverage with diminishing returns. Conclusions: Much of the population in Mozambique is unable to reach any existing immunization location, thereby reducing the potential impact of HPV vaccine. The geospatial information system analysis can assist in planning vaccine introduction strategies to maximize access and help the population reap the maximum benefits from an immunization program.

Original languageEnglish (US)
Pages (from-to)222-226
Number of pages5
JournalSexually Transmitted Diseases
Volume44
Issue number4
DOIs
StatePublished - 2017

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Mozambique
Papillomavirus Vaccines
Immunization
Economics
Health Services Needs and Demand
Population
Vaccines
Human papillomavirus 18
Immunization Programs
Cost of Illness
Human papillomavirus 16
Quality-Adjusted Life Years
Systems Analysis
Information Systems
Uterine Cervical Neoplasms
Health Care Costs
Health
Research

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Infectious Diseases

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Geospatial planning and the resulting economic impact of human papillomavirus vaccine introduction in Mozambique. / Haidari, Leila A.; Brown, Shawn T.; Constenla, Dagna; Zenkov, Eli; Ferguson, Marie; de Broucker , Gatien; Ozawa, Sachiko; Clark, Samantha; Portnoy, Allison; Lee, Bruce.

In: Sexually Transmitted Diseases, Vol. 44, No. 4, 2017, p. 222-226.

Research output: Contribution to journalArticle

Haidari, Leila A. ; Brown, Shawn T. ; Constenla, Dagna ; Zenkov, Eli ; Ferguson, Marie ; de Broucker , Gatien ; Ozawa, Sachiko ; Clark, Samantha ; Portnoy, Allison ; Lee, Bruce. / Geospatial planning and the resulting economic impact of human papillomavirus vaccine introduction in Mozambique. In: Sexually Transmitted Diseases. 2017 ; Vol. 44, No. 4. pp. 222-226.
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