Genome informatics: Current status and future prospects

Raimond L. Winslow, Mark S. Boguski

Research output: Contribution to journalReview article

Abstract

This article reviews recent advances in genomics and informatics relevant to cardiovascular research. In particular, we review the status of (1) whole genome sequencing efforts in human, mouse, rat, zebrafish, and dog; (2) the development of data mining and analysis tools; (3) the launching of the National Heart, Lung, and Blood Institute Programs for Genomics Applications and Proteomics Initiative; (4) efforts to characterize the cardiac transcriptome and proteome; and (5) the current status of computational modeling of the cardiac myocyte. In each instance, we provide links to relevant sources of information on the World Wide Web and critical appraisals of the promises and the challenges of an expanding and diverse information landscape.

Original languageEnglish (US)
Pages (from-to)953-961
Number of pages9
JournalCirculation research
Volume92
Issue number9
DOIs
StatePublished - May 16 2003

Keywords

  • Cardiovascular genomics
  • Modeling
  • Proteome
  • Transcriptome

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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