TY - JOUR
T1 - Genital warts, papillomaviruses, and genital malignancies
AU - Shah, K. V.
AU - Buscema, J.
PY - 1988
Y1 - 1988
N2 - Human papillomavirus (HPV) infections of the genital tract are widespread and often subclinical. Of about a dozen genital tract HPVs, types 16 and 18 are strongly associated with squamous cell carcinoma of the cervix and of other sites in the lower genital tract. In invasive cervical cancers, the viral genomes are often integrated into the cellular DNA and are transcriptionally active. These viruses, with additional cofactors, play a role in genital tract malignancies.
AB - Human papillomavirus (HPV) infections of the genital tract are widespread and often subclinical. Of about a dozen genital tract HPVs, types 16 and 18 are strongly associated with squamous cell carcinoma of the cervix and of other sites in the lower genital tract. In invasive cervical cancers, the viral genomes are often integrated into the cellular DNA and are transcriptionally active. These viruses, with additional cofactors, play a role in genital tract malignancies.
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U2 - 10.1146/annurev.me.39.020188.002103
DO - 10.1146/annurev.me.39.020188.002103
M3 - Review article
C2 - 2835929
AN - SCOPUS:0024216793
VL - 39
SP - 371
EP - 379
JO - Annual Review of Medicine
JF - Annual Review of Medicine
SN - 0066-4219
ER -