Genital warts, papillomaviruses, and genital malignancies

K. V. Shah; J. Buscema

doi:10.1146/annurev.me.39.020188.002103

Genital warts, papillomaviruses, and genital malignancies

K. V. Shah, J. Buscema

Bloomberg School of Public Health

Research output: Contribution to journal › Review article › peer-review

Abstract

Human papillomavirus (HPV) infections of the genital tract are widespread and often subclinical. Of about a dozen genital tract HPVs, types 16 and 18 are strongly associated with squamous cell carcinoma of the cervix and of other sites in the lower genital tract. In invasive cervical cancers, the viral genomes are often integrated into the cellular DNA and are transcriptionally active. These viruses, with additional cofactors, play a role in genital tract malignancies.

Original language	English (US)
Pages (from-to)	371-379
Number of pages	9
Journal	Annual review of medicine
Volume	39
DOIs	https://doi.org/10.1146/annurev.me.39.020188.002103
State	Published - 1988

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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title = "Genital warts, papillomaviruses, and genital malignancies",

abstract = "Human papillomavirus (HPV) infections of the genital tract are widespread and often subclinical. Of about a dozen genital tract HPVs, types 16 and 18 are strongly associated with squamous cell carcinoma of the cervix and of other sites in the lower genital tract. In invasive cervical cancers, the viral genomes are often integrated into the cellular DNA and are transcriptionally active. These viruses, with additional cofactors, play a role in genital tract malignancies.",

author = "Shah, {K. V.} and J. Buscema",

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AB - Human papillomavirus (HPV) infections of the genital tract are widespread and often subclinical. Of about a dozen genital tract HPVs, types 16 and 18 are strongly associated with squamous cell carcinoma of the cervix and of other sites in the lower genital tract. In invasive cervical cancers, the viral genomes are often integrated into the cellular DNA and are transcriptionally active. These viruses, with additional cofactors, play a role in genital tract malignancies.

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Genital warts, papillomaviruses, and genital malignancies

Abstract

ASJC Scopus subject areas

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