Genital tract infections among HIV-infected pregnant women in Malawi, Tanzania and Zambia

S. Aboud, G. Msamanga, J. S. Read, A. Mwatha, Y. Q. Chen, D. Potter, M. Valentine, U. Sharma, I. Hoffmann, T. E. Taha, R. L. Goldenberg, W. W. Fawzi

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of this study was to compare the prevalence and factors associated with genital tract infections among HIV-infected pregnant women from African sites. Participants were recruited from Blantyre and Lilongwe, Malawi; Dar es Salaam, Tanzania; and Lusaka, Zambia. Genital tract infections were assessed at baseline. Of 2627 eligible women enrolled, 2292 were HIV-infected. Of these, 47.8% had bacterial vaginosis (BV), 22.4% had vaginal candidiasis, 18.8% had trichomoniasis, 8.5% had genital warts, 2.6% had chlamydia infection, 2.2% had genital ulcers and 1.7% had gonorrhoea. The main factors associated with genital tract infections included genital warts (adjusted odds ratio [AOR] 1.8, 95% CI 1.2-2.7), genital ulcers (AOR 2.4, 95% CI 1.2-5.1) and abnormal vaginal discharge (AOR 2.5, 95% CI 1.9-3.3) for trichomoniasis. BV was the most common genital tract infection followed by candidiasis and trichomoniasis. Differences in burdens and risk factors call for enhanced interventions for identification of genital tract infections among HIV-infected women.

Original languageEnglish (US)
Pages (from-to)824-832
Number of pages9
JournalInternational Journal of STD and AIDS
Volume19
Issue number12
DOIs
StatePublished - Dec 2008

Keywords

  • Africa
  • Genital tract infections
  • Human immunodeficiency virus
  • Pregnant women
  • Sexually transmitted infections

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Pharmacology (medical)
  • Infectious Diseases

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