Genetics of diabetic nephropathy

Barbara C. Pence, Wyatt McMahon

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Accumulated evidence from family studies as well as the natural history of the development of diabetic nephropathy (DN) indicates a role for genetic determinants in overall susceptibility. However, since DN does not appear to be a monogenic disease, the search for genetic markers has been complicated. The research has included family linkage studies, candidate gene studies and more recently case-control genome-wide association studies. While the accumulated genomic data have not yielded a predictive test to this point, there are a number of promising genetic markers that will provide not only future research directions in search of a diagnostic test, but also new directions in terms of the pathogenesis of this disease.

Original languageEnglish (US)
Title of host publicationAdvances in Pathogenesis of Diabetic Nephropathy
PublisherNova Science Publishers, Inc.
Pages315-
ISBN (Print)9781611221343
StatePublished - 2011

ASJC Scopus subject areas

  • Medicine(all)

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