Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines

Samir Gupta, Dawn Provenzale, Xavier Llor, Amy L. Halverson, William Grady, Daniel C. Chung, Sigurdis Haraldsdottir, Arnold J. Markowitz, Thomas P. Slavin, Heather Hampel, Reid M. Ness, Jennifer M. Weiss, Dennis J. Ahnen, Lee May Chen, Gregory Cooper, Dayna S. Early, Francis M. Giardiello, Michael J. Hall, Stanley R. Hamilton, Priyanka KanthJason B. Klapman, Audrey J. Lazenby, Patrick M. Lynch, Robert J. Mayer, June Mikkelson, Shajan Peter, Scott E. Regenbogen, Mary A. Dwyer, Ndiya Ogba

Research output: Contribution to journalArticlepeer-review

53 Scopus citations

Abstract

Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic variants. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the assessment and management of patients with high-risk colorectal cancer syndromes. These NCCN Guidelines Insights focus on criteria for the evaluation of Lynch syndrome and considerations for use of multigene testing in the assessment of hereditary colorectal cancer syndromes.

Original languageEnglish (US)
Pages (from-to)1032-1041
Number of pages10
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume17
Issue number9
DOIs
StatePublished - 2019

ASJC Scopus subject areas

  • Oncology

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