Genetic testing and counseling for hereditary neurological diseases in Mali

Katherine Gloria Meilleur, Souleymane Coulibaly, Moussa Traoré, Guida Landouré, Alison La Pean, Modibo Sangaré, Fanny Mochel, Siona Traoré, Kenneth H. Fischbeck, Hae Ra Han

Research output: Contribution to journalArticle

Abstract

As genetic advances become incorporated into health care delivery, disparities between developing and developed countries may become greater. By addressing genetic health care needs and specific differences of developing countries, these disparities may be mitigated. We sought to describe the attitudes and knowledge of subjects with hereditary neurological diseases in Mali before and after receiving genetic testing and counseling for the first time. A questionnaire of attitudes and knowledge items was adapted and piloted for use in Mali. We found that the majority of subjects had positive attitudes toward genetic testing and counseling, both before and afterwards. Subjects responded to approximately half of the knowledge questions regarding hereditary transmission correctly before and after genetic testing and counseling. Neither overall attitudes nor knowledge scores changed significantly from baseline. Concerns about confidentiality were expressed by the majority of subjects. These findings indicate that, despite limited knowledge of patterns of inheritance, Malians understood the sensitive nature of this information and were favorable toward receiving genetic testing and counseling for diagnostic and prognostic purposes.

Original languageEnglish (US)
Pages (from-to)33-42
Number of pages10
JournalJournal of Community Genetics
Volume2
Issue number1
DOIs
StatePublished - Mar 2011

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Keywords

  • Attitudes
  • Developing countries
  • Genetic counseling
  • Genetic testing
  • Knowledge
  • West Africa

ASJC Scopus subject areas

  • Genetics(clinical)
  • Public Health, Environmental and Occupational Health
  • Epidemiology

Cite this

Meilleur, K. G., Coulibaly, S., Traoré, M., Landouré, G., Pean, A. L., Sangaré, M., Mochel, F., Traoré, S., Fischbeck, K. H., & Han, H. R. (2011). Genetic testing and counseling for hereditary neurological diseases in Mali. Journal of Community Genetics, 2(1), 33-42. https://doi.org/10.1007/s12687-011-0038-0