Genetic predisposition to multiple sclerosis as a polygenic autoimmune disease

O. O. Favorova, Alexander Favorov, A. N. Boyko, M. A. Sudomoina, T. V. Andreewski, A. D. Alekseenkov, O. G. Kulakova, E. I. Gusev, G. Parmigiani, M. F. Ochs

Research output: Contribution to journalArticle

Abstract

Unrelated patients with definite multiple sclerosis (MS) and healthy controls of Russian descent were genotyped at 16 polymorphic loci of the DRB1, TNF, LTa, TGFb1, CCR5 and CTLA4 genes and TNFa and TNFb microsatellites. The association of allelic variants with MS (p

Original languageEnglish (US)
Pages (from-to)16-22
Number of pages7
JournalZhurnal Nevrologii i Psihiatrii imeni S.S. Korsakova
Volume109
Issue number7
StatePublished - 2009
Externally publishedYes

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Keywords

  • Autoimmune hypothesis of MS pathogenesis
  • Genetics
  • Multiple sclerosis
  • Predisposing factors

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Neurology

Cite this

Favorova, O. O., Favorov, A., Boyko, A. N., Sudomoina, M. A., Andreewski, T. V., Alekseenkov, A. D., Kulakova, O. G., Gusev, E. I., Parmigiani, G., & Ochs, M. F. (2009). Genetic predisposition to multiple sclerosis as a polygenic autoimmune disease. Zhurnal Nevrologii i Psihiatrii imeni S.S. Korsakova, 109(7), 16-22.