Mapeo Genético mediante desequilibrio de ligamiento por mezcla y su aplicación en enfermedades complejas

Translated title of the contribution: Genetic mapping by means of ligament unbalance by mix and its application in complex diseases

Candelaria Vergara, Beatriz Mercedes Martínez Alfaro

Research output: Contribution to journalReview articlepeer-review

Abstract

Characterization of gens involved in complex diseases is one of greatest challenges in field of human genetics. Included in the more used strategies to this objective are studies of ligament in families, and studies of population association, using cases and controls. However, in pas years an alternative proposal is the genetic mapping method by unbalance of ligament by mix, also called "Admixture Mapping" (AM). It is an strategy that methodologically is placed among ligament studies in families and the genomic searching for association, and it is applicable in populations presenting with genetic mixture.

Translated title of the contributionGenetic mapping by means of ligament unbalance by mix and its application in complex diseases
Original languageSpanish
JournalRevista Cubana de Investigaciones Biomedicas
Volume27
Issue number2
StatePublished - Apr 1 2008
Externally publishedYes

Keywords

  • AMs
  • Ancestral marker
  • Complex diseases
  • Genomic mapping
  • Mixed populations

ASJC Scopus subject areas

  • Medicine(all)

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