Genetic make up and structure of Colombian populations by means of uniparental and biparental DNA markers

Winston Rojas, María Victoria Parra, Omer Campo, María Antonieta Caro, Juan Guillermo Lopera, William Arias, Constanza Duque, Andrés Naranjo, Jharley García, Candelaria Vergara, Jaime Lopera, Erick Hernandez, Ana Valencia, Yuri Caicedo, Mauricio Cuartas, Javier Gutiérrez, Sergio López, Andrés Ruiz-Linares, Gabriel Bedoya

Research output: Contribution to journalArticle

Abstract

Colombia is a country with great geographic heterogeneity and marked regional differences in pre-Columbian native population density and in the extent of past African and European immigration. As a result, Colombia has one of the most diverse populations in Latin America. Here we evaluated ancestry in over 1,700 individuals from 24 Colombian populations using biparental (autosomal and X-Chromosome), maternal (mtDNA), and paternal (Y-chromosome) markers. Autosomal ancestry varies markedly both within and between regions, confirming the great genetic diversity of the Colombian population. The X-chromosome, mtDNA, and Y-chromosome data indicate that there is a pattern across regions indicative of admixture involving predominantly Native American women and European and African men.

Original languageEnglish (US)
Pages (from-to)13-20
Number of pages8
JournalAmerican journal of physical anthropology
Volume143
Issue number1
DOIs
StatePublished - Sep 1 2010

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Keywords

  • Admixture
  • Colombia
  • Genetic markers
  • Mestizo

ASJC Scopus subject areas

  • Anatomy
  • Anthropology

Cite this

Rojas, W., Parra, M. V., Campo, O., Caro, M. A., Lopera, J. G., Arias, W., Duque, C., Naranjo, A., García, J., Vergara, C., Lopera, J., Hernandez, E., Valencia, A., Caicedo, Y., Cuartas, M., Gutiérrez, J., López, S., Ruiz-Linares, A., & Bedoya, G. (2010). Genetic make up and structure of Colombian populations by means of uniparental and biparental DNA markers. American journal of physical anthropology, 143(1), 13-20. https://doi.org/10.1002/ajpa.21270