Genetic dissection of synaptic transmission in Drosophila

Mark N. Wu, Hugo J. Bellen

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


Recent studies of mutations of Drosophila proteins implicated in synaptic transmission have yielded new insights into the roles of these proteins and the pathways in which they function. Analysis of mutant embryos lacking syntaxin or synaptobrevin suggests that these proteins perform distinct functions after vesicle docking with the presynaptic membrane. In addition, characterization of Drosophila endocytotic mutants provides in vivo evidence for the presence of different endocytotic pathways at a single synapse.

Original languageEnglish (US)
Pages (from-to)624-630
Number of pages7
JournalCurrent Opinion in Neurobiology
Issue number5
StatePublished - Oct 1997
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)


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