Genetic counseling outcomes

Perceived risk and distress after counseling for hereditary colorectal cancer

Ann Marie Codori, Tracy Waldeck, Gloria M. Petersen, Diana Miglioretti, Jill Brensinger Trimbath, Miriam A. Tillery

Research output: Contribution to journalArticle

Abstract

Genetic counseling may turn risk information into cancer prevention behavior by modifying health beliefs and cancer-related distress. We assessed the effect of genetic counseling on these factors in 101 adult first-degree-relatives of colorectal cancer patients from families with known or suspected hereditary nonpolyposis colorectal cancer. Before counseling and once afterward, subjects completed self-report measures of perceived lifetime risk and cancer-distress. Most persons overestimated their cancer risk, and higher perceived risk was associated with believing that colorectal cancer cannot be prevented. Individual perceived risk changed after counseling, although mean perceived risk was unchanged. After adjusting for baseline risk, older persons and those with higher estimated objective cancer risk had larger postcounseling decreases. Distress after counseling was positively correlated with baseline distress and anxiety symptoms, and inversely correlated with tolerance for ambiguity. The findings suggest counseling interventions that should increase the likelihood of screening and offer hypotheses for future research.

Original languageEnglish (US)
Pages (from-to)119-132
Number of pages14
JournalJournal of Genetic Counseling
Volume14
Issue number2
DOIs
StatePublished - Apr 2005

Fingerprint

Genetic Counseling
Counseling
Colorectal Neoplasms
Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms
Self Report
Anxiety
Health

Keywords

  • Colorectal cancer
  • Genetic counseling
  • Perceived risk
  • Psychological distress

ASJC Scopus subject areas

  • Genetics(clinical)

Cite this

Genetic counseling outcomes : Perceived risk and distress after counseling for hereditary colorectal cancer. / Codori, Ann Marie; Waldeck, Tracy; Petersen, Gloria M.; Miglioretti, Diana; Brensinger Trimbath, Jill; Tillery, Miriam A.

In: Journal of Genetic Counseling, Vol. 14, No. 2, 04.2005, p. 119-132.

Research output: Contribution to journalArticle

Codori, Ann Marie ; Waldeck, Tracy ; Petersen, Gloria M. ; Miglioretti, Diana ; Brensinger Trimbath, Jill ; Tillery, Miriam A. / Genetic counseling outcomes : Perceived risk and distress after counseling for hereditary colorectal cancer. In: Journal of Genetic Counseling. 2005 ; Vol. 14, No. 2. pp. 119-132.
@article{1f7e104bca01448a84178b39cf984c7e,
title = "Genetic counseling outcomes: Perceived risk and distress after counseling for hereditary colorectal cancer",
abstract = "Genetic counseling may turn risk information into cancer prevention behavior by modifying health beliefs and cancer-related distress. We assessed the effect of genetic counseling on these factors in 101 adult first-degree-relatives of colorectal cancer patients from families with known or suspected hereditary nonpolyposis colorectal cancer. Before counseling and once afterward, subjects completed self-report measures of perceived lifetime risk and cancer-distress. Most persons overestimated their cancer risk, and higher perceived risk was associated with believing that colorectal cancer cannot be prevented. Individual perceived risk changed after counseling, although mean perceived risk was unchanged. After adjusting for baseline risk, older persons and those with higher estimated objective cancer risk had larger postcounseling decreases. Distress after counseling was positively correlated with baseline distress and anxiety symptoms, and inversely correlated with tolerance for ambiguity. The findings suggest counseling interventions that should increase the likelihood of screening and offer hypotheses for future research.",
keywords = "Colorectal cancer, Genetic counseling, Perceived risk, Psychological distress",
author = "Codori, {Ann Marie} and Tracy Waldeck and Petersen, {Gloria M.} and Diana Miglioretti and {Brensinger Trimbath}, Jill and Tillery, {Miriam A.}",
year = "2005",
month = "4",
doi = "10.1007/s10897-005-4062-2",
language = "English (US)",
volume = "14",
pages = "119--132",
journal = "Journal of Genetic Counseling",
issn = "1059-7700",
publisher = "Kluwer Academic/Human Sciences Press Inc.",
number = "2",

}

TY - JOUR

T1 - Genetic counseling outcomes

T2 - Perceived risk and distress after counseling for hereditary colorectal cancer

AU - Codori, Ann Marie

AU - Waldeck, Tracy

AU - Petersen, Gloria M.

AU - Miglioretti, Diana

AU - Brensinger Trimbath, Jill

AU - Tillery, Miriam A.

PY - 2005/4

Y1 - 2005/4

N2 - Genetic counseling may turn risk information into cancer prevention behavior by modifying health beliefs and cancer-related distress. We assessed the effect of genetic counseling on these factors in 101 adult first-degree-relatives of colorectal cancer patients from families with known or suspected hereditary nonpolyposis colorectal cancer. Before counseling and once afterward, subjects completed self-report measures of perceived lifetime risk and cancer-distress. Most persons overestimated their cancer risk, and higher perceived risk was associated with believing that colorectal cancer cannot be prevented. Individual perceived risk changed after counseling, although mean perceived risk was unchanged. After adjusting for baseline risk, older persons and those with higher estimated objective cancer risk had larger postcounseling decreases. Distress after counseling was positively correlated with baseline distress and anxiety symptoms, and inversely correlated with tolerance for ambiguity. The findings suggest counseling interventions that should increase the likelihood of screening and offer hypotheses for future research.

AB - Genetic counseling may turn risk information into cancer prevention behavior by modifying health beliefs and cancer-related distress. We assessed the effect of genetic counseling on these factors in 101 adult first-degree-relatives of colorectal cancer patients from families with known or suspected hereditary nonpolyposis colorectal cancer. Before counseling and once afterward, subjects completed self-report measures of perceived lifetime risk and cancer-distress. Most persons overestimated their cancer risk, and higher perceived risk was associated with believing that colorectal cancer cannot be prevented. Individual perceived risk changed after counseling, although mean perceived risk was unchanged. After adjusting for baseline risk, older persons and those with higher estimated objective cancer risk had larger postcounseling decreases. Distress after counseling was positively correlated with baseline distress and anxiety symptoms, and inversely correlated with tolerance for ambiguity. The findings suggest counseling interventions that should increase the likelihood of screening and offer hypotheses for future research.

KW - Colorectal cancer

KW - Genetic counseling

KW - Perceived risk

KW - Psychological distress

UR - http://www.scopus.com/inward/record.url?scp=21544469439&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=21544469439&partnerID=8YFLogxK

U2 - 10.1007/s10897-005-4062-2

DO - 10.1007/s10897-005-4062-2

M3 - Article

VL - 14

SP - 119

EP - 132

JO - Journal of Genetic Counseling

JF - Journal of Genetic Counseling

SN - 1059-7700

IS - 2

ER -