Genetic Classification of Gliomas: Refining Histopathology

Michael B. Foote, Nickolas Papadopoulos, Luis A. Diaz

Research output: Contribution to journalShort survey

Abstract

Newly published studies validate prior reports that specific combinations of genetic alternations in IDH1/2, ATRX, TERT, TP53, and co-deletion of 1p/19q have the ability to reclassify gliomas into rational subsets, defining a glioma's biological and clinical behavior more accurately than stratifications based solely on histopathology. Newly published studies validate prior reports that specific combinations of genetic alternations in IDH1/2, ATRX, TERT, TP53, and co-deletion of 1p/19q have the ability to reclassify gliomas into rational subsets, defining a glioma's biological and clinical behavior more accurately than stratifications based solely on histopathology.

Original languageEnglish (US)
Pages (from-to)9-11
Number of pages3
JournalCancer cell
Volume28
Issue number1
DOIs
StatePublished - Jul 13 2015

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research

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