Genetic and cellular control of spontaneous autoimmune thyroiditis in OS chickens.

L. D. Bacon; R. S. Sundick; N. R. Rose

doi:10.1007/978-1-4613-4169-7_29

Genetic and cellular control of spontaneous autoimmune thyroiditis in OS chickens.

L. D. Bacon, R. S. Sundick, N. R. Rose

School of Medicine

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7 Scopus citations

Abstract

B-locus genotypes have been defined in Obese strain (OS) chickens that spontaneously develop autoimmune thyroiditis (SAT), and in White Leghorn Cornell C strain (CS) chickens from which the OS was selected. The B-locus influences SAT, and some possible mechanisms are discussed. Thymic abnormalities in OS, as contrasted with CB birds, are also discussed and may play a role in SAT, as may an intrinsic defect in the thyroid gland itself.

Original language	English (US)
Pages (from-to)	309-318
Number of pages	10
Journal	Advances in experimental medicine and biology
Volume	88
DOIs	https://doi.org/10.1007/978-1-4613-4169-7_29
State	Published - 1977

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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abstract = "B-locus genotypes have been defined in Obese strain (OS) chickens that spontaneously develop autoimmune thyroiditis (SAT), and in White Leghorn Cornell C strain (CS) chickens from which the OS was selected. The B-locus influences SAT, and some possible mechanisms are discussed. Thymic abnormalities in OS, as contrasted with CB birds, are also discussed and may play a role in SAT, as may an intrinsic defect in the thyroid gland itself.",

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AU - Sundick, R. S.

AU - Rose, N. R.

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AB - B-locus genotypes have been defined in Obese strain (OS) chickens that spontaneously develop autoimmune thyroiditis (SAT), and in White Leghorn Cornell C strain (CS) chickens from which the OS was selected. The B-locus influences SAT, and some possible mechanisms are discussed. Thymic abnormalities in OS, as contrasted with CB birds, are also discussed and may play a role in SAT, as may an intrinsic defect in the thyroid gland itself.

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ER -

Genetic and cellular control of spontaneous autoimmune thyroiditis in OS chickens.

Abstract

ASJC Scopus subject areas

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