Abstract
B-locus genotypes have been defined in Obese strain (OS) chickens that spontaneously develop autoimmune thyroiditis (SAT), and in White Leghorn Cornell C strain (CS) chickens from which the OS was selected. The B-locus influences SAT, and some possible mechanisms are discussed. Thymic abnormalities in OS, as contrasted with CB birds, are also discussed and may play a role in SAT, as may an intrinsic defect in the thyroid gland itself.
Original language | English (US) |
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Pages (from-to) | 309-318 |
Number of pages | 10 |
Journal | Advances in experimental medicine and biology |
Volume | 88 |
DOIs | |
State | Published - 1977 |
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology