Abstract
A 13 X-chromosomal short tandem repeat (STR) multiplex system (DXS6807, DXS8378, DSX9902, DXS7132, DXS9898, DXS6809, DXS6789, DXS7424, DXS101, GATA172D05, HPRTB, DXS8377, and DXS7423) was tested on 1,037 DNA samples from eight population groups currently living in Taiwan. Different distributions of the allelic frequencies in different populations were presented. DXS8377 and DXS101 were the two most polymorphic loci in these eight populations, whereas DXS7423 was the least informative marker in most of the populations studied. The genetic distances between the populations and the constructed phylogenetic tree revealed a long genetic distance between Asian and Caucasian populations as well as isolation of the Tao population. The phylogenetic tree grouped populations into clusters compatible with their ethnogeographic relationships. This 13 X-chromosomal short tandem repeat multiplex system offers a considerable number of polymorphic patterns in different populations. This system can be useful in forensic identification casework and ethnogeographic research.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 33-37 |
| Number of pages | 5 |
| Journal | International Journal of Legal Medicine |
| Volume | 125 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2011 |
| Externally published | Yes |
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Keywords
- Forensic identification
- Genetic distance
- Multiplex PCR
- Phylogenetic tree
- Short tandem repeat
- X chromosome
ASJC Scopus subject areas
- Pathology and Forensic Medicine
Cite this
Genetic analysis of eight population groups living in Taiwan using a 13 X-chromosomal STR loci multiplex system. / Hwa, Hsiao Lin; Lee, James Chun I; Chang, Yih Yuan; Yin, Hsiang Yi; Chen, Ya Hui; Tseng, Li Hui; Su, Yi Ning; Ko, Tsang Ming.
In: International Journal of Legal Medicine, Vol. 125, No. 1, 01.2011, p. 33-37.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Genetic analysis of eight population groups living in Taiwan using a 13 X-chromosomal STR loci multiplex system
AU - Hwa, Hsiao Lin
AU - Lee, James Chun I
AU - Chang, Yih Yuan
AU - Yin, Hsiang Yi
AU - Chen, Ya Hui
AU - Tseng, Li Hui
AU - Su, Yi Ning
AU - Ko, Tsang Ming
PY - 2011/1
Y1 - 2011/1
N2 - A 13 X-chromosomal short tandem repeat (STR) multiplex system (DXS6807, DXS8378, DSX9902, DXS7132, DXS9898, DXS6809, DXS6789, DXS7424, DXS101, GATA172D05, HPRTB, DXS8377, and DXS7423) was tested on 1,037 DNA samples from eight population groups currently living in Taiwan. Different distributions of the allelic frequencies in different populations were presented. DXS8377 and DXS101 were the two most polymorphic loci in these eight populations, whereas DXS7423 was the least informative marker in most of the populations studied. The genetic distances between the populations and the constructed phylogenetic tree revealed a long genetic distance between Asian and Caucasian populations as well as isolation of the Tao population. The phylogenetic tree grouped populations into clusters compatible with their ethnogeographic relationships. This 13 X-chromosomal short tandem repeat multiplex system offers a considerable number of polymorphic patterns in different populations. This system can be useful in forensic identification casework and ethnogeographic research.
AB - A 13 X-chromosomal short tandem repeat (STR) multiplex system (DXS6807, DXS8378, DSX9902, DXS7132, DXS9898, DXS6809, DXS6789, DXS7424, DXS101, GATA172D05, HPRTB, DXS8377, and DXS7423) was tested on 1,037 DNA samples from eight population groups currently living in Taiwan. Different distributions of the allelic frequencies in different populations were presented. DXS8377 and DXS101 were the two most polymorphic loci in these eight populations, whereas DXS7423 was the least informative marker in most of the populations studied. The genetic distances between the populations and the constructed phylogenetic tree revealed a long genetic distance between Asian and Caucasian populations as well as isolation of the Tao population. The phylogenetic tree grouped populations into clusters compatible with their ethnogeographic relationships. This 13 X-chromosomal short tandem repeat multiplex system offers a considerable number of polymorphic patterns in different populations. This system can be useful in forensic identification casework and ethnogeographic research.
KW - Forensic identification
KW - Genetic distance
KW - Multiplex PCR
KW - Phylogenetic tree
KW - Short tandem repeat
KW - X chromosome
UR - http://www.scopus.com/inward/record.url?scp=78651334407&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78651334407&partnerID=8YFLogxK
U2 - 10.1007/s00414-009-0414-z
DO - 10.1007/s00414-009-0414-z
M3 - Article
C2 - 20428882
AN - SCOPUS:78651334407
VL - 125
SP - 33
EP - 37
JO - International Journal of Legal Medicine
JF - International Journal of Legal Medicine
SN - 0937-9827
IS - 1
ER -