Generation and characterization of ABBV642, a dual variable domain immunoglobulin molecule (DVD-Ig) that potently neutralizes VEGF and PDGF-BB and is designed for the treatment of exudative age-related macular degeneration

Kun Ding, Lucia Eaton, Diana Bowley, Matthew Rieser, Qing Chang, Maria C. Harris, Anca Clabbers, Feng Dong, Jikui Shen, Sean F. Hackett, Debra S. Touw, Jacqueline Bixby, Suju Zhong, Lorenzo Benatuil, Sahana Bose, Christine Grinnell, Gregory M. Preston, Ramesh Iyer, Ramkrishna Sadhukhan, Susan MarchieGary Overmeyer, Tariq Ghayur, Deborah A. van Riet, Shibo Tang, Peter A. Campochario, Jijie Gu

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Medicine & Life Sciences