Generating patient-specific dosimetry phantoms with whole-body diffeomorphic image registration

D. J. Tward; C. Ceritoglu; G. Sturgeon; W. P. Segars; M. I. Miller; J. T. Ratnanather

doi:10.1109/NEBC.2011.5778717

Generating patient-specific dosimetry phantoms with whole-body diffeomorphic image registration

D. J. Tward, C. Ceritoglu, G. Sturgeon, W. P. Segars, M. I. Miller, J. T. Ratnanather

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

8 Scopus citations

Abstract

This work describes a protocol for creating a population of pediatric, patient specific, computational dosimetry phantoms. Pediatric CT data are mapped to a detailed adult template using multi channel (MC) - large deformation diffeomorphic metric mapping (LDDMM) applied to whole body images. Challenges are studied and overcome using 2D LDDMM applied to simulated phantoms. The protocol involves automatic placement of landmarks, landmark based affine and LDDMM registration, followed by 4 applications of MC-LDDMM, with successively decreasing smoothness constraints. Deformed adult organ surfaces typically agree with pediatric organ surfaces within 1-2 voxels (∼2.3 mm).

Original language	English (US)
Title of host publication	2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011
DOIs	https://doi.org/10.1109/NEBC.2011.5778717
State	Published - 2011
Externally published	Yes
Event	37th Annual Northeast Bioengineering Conference, NEBEC 2011 - Troy, NY, United States Duration: Apr 1 2011 → Apr 3 2011

Publication series

Name	2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011

Other

Other	37th Annual Northeast Bioengineering Conference, NEBEC 2011
Country/Territory	United States
City	Troy, NY
Period	4/1/11 → 4/3/11

ASJC Scopus subject areas

Bioengineering

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10.1109/NEBC.2011.5778717

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Tward, D. J., Ceritoglu, C., Sturgeon, G., Segars, W. P., Miller, M. I., & Ratnanather, J. T. (2011). Generating patient-specific dosimetry phantoms with whole-body diffeomorphic image registration. In 2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011 Article 5778717 (2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011). https://doi.org/10.1109/NEBC.2011.5778717

Generating patient-specific dosimetry phantoms with whole-body diffeomorphic image registration. / Tward, D. J.; Ceritoglu, C.; Sturgeon, G. et al.
2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011. 2011. 5778717 (2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Tward, DJ, Ceritoglu, C, Sturgeon, G, Segars, WP, Miller, MI & Ratnanather, JT 2011, Generating patient-specific dosimetry phantoms with whole-body diffeomorphic image registration. in 2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011., 5778717, 2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011, 37th Annual Northeast Bioengineering Conference, NEBEC 2011, Troy, NY, United States, 4/1/11. https://doi.org/10.1109/NEBC.2011.5778717

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Generating patient-specific dosimetry phantoms with whole-body diffeomorphic image registration

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