TY - JOUR
T1 - Genealogy of centenarians and their relatives
T2 - A study of 12 families
AU - Motta, M.
AU - Malaguarnera, M.
AU - Ferrari, E.
AU - Mauro, V. Nicita
AU - Ferrucci, L.
AU - Rapisarda, R.
AU - Tomasello, F. B.
AU - Basile, G.
AU - Ferlito, L.
AU - Passamonte, M.
AU - Bennati, E.
PY - 2007/7
Y1 - 2007/7
N2 - The longevity is a complex phenomenon in which specific genetic properties seem to play a role. The present study intended to reconstruct the genealogical tree of 12 subjects, being residents of one Northern and one Southern province of Italy, in order to establish the longevity of the ancestors. Detailed studies have been performed in the registry offices and the historic archives. The research method started from the identification of the centenarians on the basis of the documentation of the relevant birth document, it was continued by identifying the documents of birth, marriages and death of the parents of the centenarians. This way we proceeded systematically backwards in time. In addition, we verified the medium life span of the Italian population in the given periods of time, when the centenarians and their ascending lines had lived. These results offer clear historic-statistical evidences for the genetic basis of longevity.
AB - The longevity is a complex phenomenon in which specific genetic properties seem to play a role. The present study intended to reconstruct the genealogical tree of 12 subjects, being residents of one Northern and one Southern province of Italy, in order to establish the longevity of the ancestors. Detailed studies have been performed in the registry offices and the historic archives. The research method started from the identification of the centenarians on the basis of the documentation of the relevant birth document, it was continued by identifying the documents of birth, marriages and death of the parents of the centenarians. This way we proceeded systematically backwards in time. In addition, we verified the medium life span of the Italian population in the given periods of time, when the centenarians and their ascending lines had lived. These results offer clear historic-statistical evidences for the genetic basis of longevity.
KW - Genealogical tree of centenarians
KW - Genetic basis of longevity
KW - Medium life span of the Italian population
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U2 - 10.1016/j.archger.2006.10.004
DO - 10.1016/j.archger.2006.10.004
M3 - Article
C2 - 17196681
AN - SCOPUS:34247606832
SN - 0167-4943
VL - 45
SP - 97
EP - 102
JO - Archives of Gerontology and Geriatrics
JF - Archives of Gerontology and Geriatrics
IS - 1
ER -