The human genome is estimated to contain 35,000 genes (Lander et al., 2001). In all eukaryotic cells, the expression of a gene that encodes a protein proceeds in several steps: the gene is transcribed, the RNA product is processed and transported out of the nucleus, and the mature messenger RNA (mRNA) is translated into protein. Genes are regulated in their expression at different developmental stages, body regions, and physiologic states. For a variety of human diseases, gene expression varies as a function of a pathologic condition. This chapter reviews the role of gene expression in autism.
|Original language||English (US)|
|Title of host publication||The Neurobiology of Autism|
|Publisher||The Johns Hopkins University Press|
|Number of pages||10|
|State||Published - Dec 1 2005|
ASJC Scopus subject areas
- Social Sciences(all)