Gender and survival after AIDS in Rio de Janeiro, Brazil

Guilherme Santoro-Lopes, Lee H. Harrison, Lawrence H. Moulton, Luis Antonio Alves Lima, Ana Maria Felix De Pinho, Cristina Hofer, Mauro Schechter

Research output: Contribution to journalArticle

Abstract

The relation between gender and survival after a diagnosis of AIDS was studied in a cohort of patients with HIV infection in Rio de Janeiro, Brazil. During the study period, 124 of 617 patients (20%) developed AIDS. Of this group, 91 patients were men and 33 were women. There were no gender related differences regarding the access to antiretroviral therapy or to prophylaxis for Pneumocystis carinii pneumonia. Survival was shorter among women (hazard ratio [HR] = 4.43; p < .001) after adjustment for age and AIDS-defining condition. Adjusting for CD4+ and CD8+ counts reduced the difference between genders (HR = 3.33; p = .017). These results suggest that survival after an AIDS diagnosis may be shorter among women than men in Brazil. Further studies are needed to determine the factors that may be negatively influencing the prognosis of women with AIDS in Brazil.

Original languageEnglish (US)
Pages (from-to)403-407
Number of pages5
JournalJournal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Volume19
Issue number4
DOIs
StatePublished - Dec 1 1998

Keywords

  • AIDS
  • CD4 and CD8 lymphocyte counts
  • Gender
  • HIV
  • Survival analysis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Virology

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