Abstract
We examined the effects of prenatal exposure (40 min/day, gestation days 12-18) of rats to a magnetic resonance imaging (MRI) magnetic field (MF) on their performance in the Morris water maze. At 2 months of age, female rats showed impaired performance. The animals spent longer time swimming and used inefficient strategies. However, no significant effects on maze performance were observed at 1 and 5 months of age. No evident maze performance deficit was detected in male rats prenatally exposed to the magnetic field. Thus, we conclude that prenatal exposure to MRI magnetic field induces cognitive/behavioral deficits in female rats at a specific age.
Original language | English (US) |
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Pages (from-to) | 140-144 |
Number of pages | 5 |
Journal | Brain research |
Volume | 995 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2 2004 |
Externally published | Yes |
Keywords
- Magnetic field
- Magnetic resonance imaging
- Morris water maze
- Prenatal exposure
- Sexual difference
- Spatial learning
ASJC Scopus subject areas
- General Neuroscience
- Molecular Biology
- Clinical Neurology
- Developmental Biology