Gastrointestinal Lesions in African American Patients With Iron Deficiency Anemia

Hassan Brim, Anahita Shahnazi, Mehdi Nouraie, Dilhana Badurdeen, Adeyinka O. Laiyemo, Tahmineh Haidary, Ali Afsari, Hassan Ashktorab

Research output: Contribution to journalArticle

Abstract

Background: Iron deficiency anemia (IDA) is a frequent disorder that is associated with many serious diseases. However, the findings of an evaluation of IDA-associated gastrointestinal disorders are lacking among African American patients. Aim: To determine the most prevalent gastrointestinal lesions among African American patients with IDA especially in young men. Methods: We reviewed medical records (n = 422) of patients referred for evaluation of IDA from 2008 to 2012. Iron deficiency anemia was diagnosed using clinical laboratory tests. The results of esophagogastroduodenoscopy, colonoscopy, and pathology specimens along with demographic data were abstracted and analyzed using Stata. Results: The mean age was 61.9 years, and 50.5% were women. In total, 189 patients (45%) had gross gastrointestinal (GI) bleeding. The most frequent diagnoses were gastritis (40%), benign colonic lesions (13%), esophagitis (9%), gastric ulcer (6%), and duodenitis (6%). GI bleeding was significantly more frequent in men (P = 0.001). Benign and malignant colonic lesions were significantly more present among older patients: 16% vs 6% (P =.005) and 5% vs 0% (P =.008), respectively. Colitis was more prevalent in younger patients (⩽50): 11% vs 2% (P =.001). In patients with gross lower GI bleeding, the top diagnoses were gastritis (25%), benign colon tumors (10%), and duodenitis (6%). Colon cancer was diagnosed among 15 patients, and all these patients were older than 50 years of age. Conclusions: Gastritis and colonic lesions are most common associated lesions with IDA among African Americans. So bidirectional endoscopy is required for unrevealing of the cause of IDA in asymptomatic patients.

Original languageEnglish (US)
JournalClinical Medicine Insights: Gastroenterology
Volume11
DOIs
StatePublished - May 17 2018
Externally publishedYes

Fingerprint

Iron-Deficiency Anemias
African Americans
Gastritis
Duodenitis
Hemorrhage
Digestive System Endoscopy
Esophagitis
Colitis
Colonoscopy
Stomach Ulcer
Colonic Neoplasms
Endoscopy
Medical Records
Colon
Demography
Pathology

Keywords

  • EGD and colonoscopy
  • GI lesions
  • Iron deficiency anemia

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Gastrointestinal Lesions in African American Patients With Iron Deficiency Anemia. / Brim, Hassan; Shahnazi, Anahita; Nouraie, Mehdi; Badurdeen, Dilhana; Laiyemo, Adeyinka O.; Haidary, Tahmineh; Afsari, Ali; Ashktorab, Hassan.

In: Clinical Medicine Insights: Gastroenterology, Vol. 11, 17.05.2018.

Research output: Contribution to journalArticle

Brim, Hassan ; Shahnazi, Anahita ; Nouraie, Mehdi ; Badurdeen, Dilhana ; Laiyemo, Adeyinka O. ; Haidary, Tahmineh ; Afsari, Ali ; Ashktorab, Hassan. / Gastrointestinal Lesions in African American Patients With Iron Deficiency Anemia. In: Clinical Medicine Insights: Gastroenterology. 2018 ; Vol. 11.
@article{8555cde181584e42a487f0961f355c6f,
title = "Gastrointestinal Lesions in African American Patients With Iron Deficiency Anemia",
abstract = "Background: Iron deficiency anemia (IDA) is a frequent disorder that is associated with many serious diseases. However, the findings of an evaluation of IDA-associated gastrointestinal disorders are lacking among African American patients. Aim: To determine the most prevalent gastrointestinal lesions among African American patients with IDA especially in young men. Methods: We reviewed medical records (n = 422) of patients referred for evaluation of IDA from 2008 to 2012. Iron deficiency anemia was diagnosed using clinical laboratory tests. The results of esophagogastroduodenoscopy, colonoscopy, and pathology specimens along with demographic data were abstracted and analyzed using Stata. Results: The mean age was 61.9 years, and 50.5{\%} were women. In total, 189 patients (45{\%}) had gross gastrointestinal (GI) bleeding. The most frequent diagnoses were gastritis (40{\%}), benign colonic lesions (13{\%}), esophagitis (9{\%}), gastric ulcer (6{\%}), and duodenitis (6{\%}). GI bleeding was significantly more frequent in men (P = 0.001). Benign and malignant colonic lesions were significantly more present among older patients: 16{\%} vs 6{\%} (P =.005) and 5{\%} vs 0{\%} (P =.008), respectively. Colitis was more prevalent in younger patients (⩽50): 11{\%} vs 2{\%} (P =.001). In patients with gross lower GI bleeding, the top diagnoses were gastritis (25{\%}), benign colon tumors (10{\%}), and duodenitis (6{\%}). Colon cancer was diagnosed among 15 patients, and all these patients were older than 50 years of age. Conclusions: Gastritis and colonic lesions are most common associated lesions with IDA among African Americans. So bidirectional endoscopy is required for unrevealing of the cause of IDA in asymptomatic patients.",
keywords = "EGD and colonoscopy, GI lesions, Iron deficiency anemia",
author = "Hassan Brim and Anahita Shahnazi and Mehdi Nouraie and Dilhana Badurdeen and Laiyemo, {Adeyinka O.} and Tahmineh Haidary and Ali Afsari and Hassan Ashktorab",
year = "2018",
month = "5",
day = "17",
doi = "10.1177/1179552218778627",
language = "English (US)",
volume = "11",
journal = "Clinical Medicine Insights: Gastroenterology",
issn = "1179-5522",
publisher = "Libertas Academica Ltd.",

}

TY - JOUR

T1 - Gastrointestinal Lesions in African American Patients With Iron Deficiency Anemia

AU - Brim, Hassan

AU - Shahnazi, Anahita

AU - Nouraie, Mehdi

AU - Badurdeen, Dilhana

AU - Laiyemo, Adeyinka O.

AU - Haidary, Tahmineh

AU - Afsari, Ali

AU - Ashktorab, Hassan

PY - 2018/5/17

Y1 - 2018/5/17

N2 - Background: Iron deficiency anemia (IDA) is a frequent disorder that is associated with many serious diseases. However, the findings of an evaluation of IDA-associated gastrointestinal disorders are lacking among African American patients. Aim: To determine the most prevalent gastrointestinal lesions among African American patients with IDA especially in young men. Methods: We reviewed medical records (n = 422) of patients referred for evaluation of IDA from 2008 to 2012. Iron deficiency anemia was diagnosed using clinical laboratory tests. The results of esophagogastroduodenoscopy, colonoscopy, and pathology specimens along with demographic data were abstracted and analyzed using Stata. Results: The mean age was 61.9 years, and 50.5% were women. In total, 189 patients (45%) had gross gastrointestinal (GI) bleeding. The most frequent diagnoses were gastritis (40%), benign colonic lesions (13%), esophagitis (9%), gastric ulcer (6%), and duodenitis (6%). GI bleeding was significantly more frequent in men (P = 0.001). Benign and malignant colonic lesions were significantly more present among older patients: 16% vs 6% (P =.005) and 5% vs 0% (P =.008), respectively. Colitis was more prevalent in younger patients (⩽50): 11% vs 2% (P =.001). In patients with gross lower GI bleeding, the top diagnoses were gastritis (25%), benign colon tumors (10%), and duodenitis (6%). Colon cancer was diagnosed among 15 patients, and all these patients were older than 50 years of age. Conclusions: Gastritis and colonic lesions are most common associated lesions with IDA among African Americans. So bidirectional endoscopy is required for unrevealing of the cause of IDA in asymptomatic patients.

AB - Background: Iron deficiency anemia (IDA) is a frequent disorder that is associated with many serious diseases. However, the findings of an evaluation of IDA-associated gastrointestinal disorders are lacking among African American patients. Aim: To determine the most prevalent gastrointestinal lesions among African American patients with IDA especially in young men. Methods: We reviewed medical records (n = 422) of patients referred for evaluation of IDA from 2008 to 2012. Iron deficiency anemia was diagnosed using clinical laboratory tests. The results of esophagogastroduodenoscopy, colonoscopy, and pathology specimens along with demographic data were abstracted and analyzed using Stata. Results: The mean age was 61.9 years, and 50.5% were women. In total, 189 patients (45%) had gross gastrointestinal (GI) bleeding. The most frequent diagnoses were gastritis (40%), benign colonic lesions (13%), esophagitis (9%), gastric ulcer (6%), and duodenitis (6%). GI bleeding was significantly more frequent in men (P = 0.001). Benign and malignant colonic lesions were significantly more present among older patients: 16% vs 6% (P =.005) and 5% vs 0% (P =.008), respectively. Colitis was more prevalent in younger patients (⩽50): 11% vs 2% (P =.001). In patients with gross lower GI bleeding, the top diagnoses were gastritis (25%), benign colon tumors (10%), and duodenitis (6%). Colon cancer was diagnosed among 15 patients, and all these patients were older than 50 years of age. Conclusions: Gastritis and colonic lesions are most common associated lesions with IDA among African Americans. So bidirectional endoscopy is required for unrevealing of the cause of IDA in asymptomatic patients.

KW - EGD and colonoscopy

KW - GI lesions

KW - Iron deficiency anemia

UR - http://www.scopus.com/inward/record.url?scp=85055162187&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85055162187&partnerID=8YFLogxK

U2 - 10.1177/1179552218778627

DO - 10.1177/1179552218778627

M3 - Article

C2 - 29795991

AN - SCOPUS:85055162187

VL - 11

JO - Clinical Medicine Insights: Gastroenterology

JF - Clinical Medicine Insights: Gastroenterology

SN - 1179-5522

ER -