Gastrointestinal and Hepatic Disease in Rheumatoid Arthritis

Ethan Craig, Laura Cappelli

Research output: Contribution to journalReview article

Abstract

Gastrointestinal (GI) manifestations of rheumatoid arthritis (RA) are rare, but can be impactful for patients. Some GI processes are directly related to RA, whereas others may be sequelae of treatment or caused by concomitant autoimmune diseases. This article discusses the role of the GI tract in RA pathogenesis; the presentation, epidemiology, and diagnosis of RA-related GI manifestations; concomitant GI autoimmune diseases that may affect those with RA; and GI side effects of RA treatment. The importance of appropriately considering conditions unrelated to RA in the differential diagnosis when evaluating new GI symptoms in patients with RA is noted.

Original languageEnglish (US)
Pages (from-to)89-111
Number of pages23
JournalRheumatic Disease Clinics of North America
Volume44
Issue number1
DOIs
StatePublished - Feb 1 2018

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Keywords

  • Antirheumatic medications (DMARDs)
  • Gastrointestinal disease
  • Hepatic disease
  • Rheumatoid arthritis

ASJC Scopus subject areas

  • Rheumatology

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