Gastric myoelectrical activity in healthy children and children with functional dyspepsia

Jiande Chen, Xuemei Lin, Ming Zhang, Ramon B. Torres-Pinedo, William C. Orr

Research output: Contribution to journalArticle

Abstract

The aim of this study was to investigate abnormalities in pediatric patients with functional dyspepsia. Fifteen symptomatic pediatric patients diagnosed with functional dyspepsia and 17 aged-matched healthy controls were studied. Gastric myoelectrical activity was recorded using surface; electrogastrography for 1 hr in the fasting state and 1 hr after a test meal. It was found that, in comparison with the controls, the children with functional dyspepsia had a lower percentage of 2- to 4-cpm slow waves in both fasting state (66.0 ± 4.7% vs 79.7 ± 3.1%, P <0.07) and fed state (72.4 ± 5.4% vs 85.0 ± 2.9%, P <0.04), and a significantly higher instability of the dominant frequency in both fasting state (0.50 ± 0.05 vs 0.31 ± 0.04, P <0.01) and fed state (0.39 ± 0.05 vs 0.25 ± 0.03, P <0.05). It was also found the postprandial increase in EGG dominant power in the patients was inversely correlated with the total symptom score (r = 0.63, P = 0.03). It was concluded that abnormal gastric myoelectrical activity may play a role in the pathogenesis of pediatric functional dyspepsia.

Original languageEnglish (US)
Pages (from-to)2384-2391
Number of pages8
JournalDigestive Diseases and Sciences
Volume43
Issue number11
StatePublished - 1998
Externally publishedYes

Fingerprint

Dyspepsia
Stomach
Fasting
Pediatrics
Ovum
Meals

Keywords

  • Electrogastrography
  • Functional dyspepsia
  • Gastric emptying
  • Gastrointestinal motility

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Chen, J., Lin, X., Zhang, M., Torres-Pinedo, R. B., & Orr, W. C. (1998). Gastric myoelectrical activity in healthy children and children with functional dyspepsia. Digestive Diseases and Sciences, 43(11), 2384-2391.

Gastric myoelectrical activity in healthy children and children with functional dyspepsia. / Chen, Jiande; Lin, Xuemei; Zhang, Ming; Torres-Pinedo, Ramon B.; Orr, William C.

In: Digestive Diseases and Sciences, Vol. 43, No. 11, 1998, p. 2384-2391.

Research output: Contribution to journalArticle

Chen, J, Lin, X, Zhang, M, Torres-Pinedo, RB & Orr, WC 1998, 'Gastric myoelectrical activity in healthy children and children with functional dyspepsia', Digestive Diseases and Sciences, vol. 43, no. 11, pp. 2384-2391.
Chen, Jiande ; Lin, Xuemei ; Zhang, Ming ; Torres-Pinedo, Ramon B. ; Orr, William C. / Gastric myoelectrical activity in healthy children and children with functional dyspepsia. In: Digestive Diseases and Sciences. 1998 ; Vol. 43, No. 11. pp. 2384-2391.
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