Gait pattern alterations in older adults associated with type 2 diabetes in the absence of peripheral neuropathy-Results from the Baltimore Longitudinal Study of Aging

Seung uk Ko, Sari Stenholm, Chee W. Chia, Eleanor Marie Simonsick, Luigi Ferrucci

Research output: Contribution to journalArticle

Abstract

Diabetes may impact gait mechanics before onset of frank neuropathies and other associated threats to mobility. This study aims to characterize gait pattern alterations of type 2 diabetic adults without peripheral neuropathy during walking at maximum speed (fast-walking) as well as at self-selected speed (usual-walking). One-hundred and eighty-six participants aged 60-87 from the Baltimore Longitudinal Study of Aging (BLSA) able to walk unassisted and without peripheral neuropathy were classified as non-diabetic (N=160) or having type 2 diabetes (N=26). Gait parameters from the fast-walking and usual-walking tests were compared between participants with and without type 2 diabetes. Participants with diabetes had a shorter stride length for fast-walking (p=0.033) and a longer percentage of the gait cycle with the knee in 1st flexion for both fast- and usual-walking (p=0.033, and 0.040, respectively) than non-diabetic participants. Participants with diabetes exhibited a smaller hip range of motion in the sagittal plane during usual-walking compared to non-diabetics (p=0.049). During fast-walking, participants with diabetes used lower ankle generative mechanical work expenditure (MWE) and higher knee absorptive MWE compared to non-diabetic persons (p=0.021, and 0.018, respectively). These findings suggest that individuals with type 2 diabetes without overt peripheral neuropathy exhibit altered and less efficient gait patterns than non-diabetic persons. These alterations are more apparent during walking at a maximum speed indicating that maximum gait testing may be useful for identifying early threats to mobility limitations in older adults with type 2 diabetes.

Original languageEnglish (US)
Pages (from-to)548-552
Number of pages5
JournalGait and Posture
Volume34
Issue number4
DOIs
StatePublished - Oct 2011
Externally publishedYes

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Keywords

  • Aging
  • Gait
  • Mechanical work expenditure
  • Mobility limitation
  • Peripheral neuropathy
  • Type 2 diabetes

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Rehabilitation
  • Biophysics

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