Future trends in antimicrobial chemotherapy: Expert opinion on the 43 rd ICAAC

A. P. Ball, John Bartlett, W. A. Craig, G. L. Drusano, D. Felmingham, J. A. Garau, K. P. Klugman, D. E. Low, L. A. Mandell, E. Rubinstein, G. S. Tillotson

Research output: Contribution to journalArticle

Abstract

The current document bestows an expert synopsis of key new information presented at the 43 rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) meeting in 2003. Data is presented on the socio-political aspects of and policies on antimicrobial prescribing, novel mechanisms of resistance in Streptococcus pneumoniae, and current epidemiological trends in global resistance. Novel information on new (and existing) antimicrobial agents - new penicillins, cephalosporins, monobactams and oxipenem inhibitors, ketolides, glycopeptides, fluoroquinolones (and hybrids), peptides, daptomycin, aminomethylcyclines, glycylcyclines, and newer formulations of agents such as amoxycillin-clavulanate - provides renewed hope that resistant pathogens can be controlled through use of more potent agents. Improved strategies for the use of existing antimicrobial agents, such as the use of high-dose regimens, short-course therapy, also may delay or reduce the development of resistance and preserve the value of our antibiotic armamentarium.

Original languageEnglish (US)
Pages (from-to)419-436
Number of pages18
JournalJournal of Chemotherapy
Volume16
Issue number5
Publication statusPublished - Oct 2004

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Keywords

  • Antimicrobial resistance
  • Appropriate use
  • Beta-lactams
  • Clinical trials
  • Fluoroquinolones
  • Immunomodulation
  • Ketolides
  • Macrolides
  • Oxazolidinones

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Microbiology (medical)

Cite this

Ball, A. P., Bartlett, J., Craig, W. A., Drusano, G. L., Felmingham, D., Garau, J. A., ... Tillotson, G. S. (2004). Future trends in antimicrobial chemotherapy: Expert opinion on the 43 rd ICAAC. Journal of Chemotherapy, 16(5), 419-436.