Future perspectives for regenerative medicine in ophthalmology

Jennifer Elisseeff, Marcos G. Madrid, Qiaozhi Lu, J. Jeremy Chae, Qiongyu Guo

Research output: Contribution to journalArticlepeer-review

Abstract

Repair and reconstruction of the cornea has historically relied on synthetic materials or tissue transplantation. However, the future holds promise for treatments using smart biomaterials and stem cells that direct tissue repair and regeneration to ultimately create new ocular structures that are indistinguishable from the original native tissue. The cornea is a remarkable engineering structure. By understanding the physical structure of the tissue and the resulting impact of the structure on biological function, we can design novel materials for a number of ophthalmic clinical applications. Furthermore, by extending this structure-function approach to characterizing corneal disease processes, new therapies can be engineered.

Original languageEnglish (US)
Pages (from-to)38-45
Number of pages8
JournalMiddle East African Journal of Ophthalmology
Volume20
Issue number1
DOIs
StatePublished - Jan 2013

Keywords

  • Biomaterials
  • cornea
  • stem cells
  • therapies

ASJC Scopus subject areas

  • Ophthalmology

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